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rsv a2  (ATCC)


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    Structured Review

    ATCC rsv a2
    ChAd68-PreF elicits robust <t>anti-RSV</t> F binding IgG responses in cotton rats. (A), immunization and challenge schedule. Animals received a homologous prime-boost (day 0 and 28) and were intranasally challenged with 1 × 10 5 PFU RSV <t>A2</t> on day 56, except the unchallenged ChAd68-GFP/UnCh group. (B), Serum binding IgG antibody titers (ELISA) at days 0, 28, 56 and 61. The symbols denote individual animals; bars show mean ± SD. Statistics: one-way ANOVA with Tukey’s multiple-comparisons test (* p < .05; ** p < .01; *** p < .001; **** p < .0001).
    Rsv A2, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 452 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rsv a2/product/ATCC
    Average 97 stars, based on 452 article reviews
    rsv a2 - by Bioz Stars, 2026-03
    97/100 stars

    Images

    1) Product Images from "Mucosal immunization with an adenoviral vector expressing a prefusogenic F protein protects the upper and lower respiratory tracts of cotton rats against live respiratory syncytial virus challenge"

    Article Title: Mucosal immunization with an adenoviral vector expressing a prefusogenic F protein protects the upper and lower respiratory tracts of cotton rats against live respiratory syncytial virus challenge

    Journal: Human Vaccines & Immunotherapeutics

    doi: 10.1080/21645515.2026.2623573

    ChAd68-PreF elicits robust anti-RSV F binding IgG responses in cotton rats. (A), immunization and challenge schedule. Animals received a homologous prime-boost (day 0 and 28) and were intranasally challenged with 1 × 10 5 PFU RSV A2 on day 56, except the unchallenged ChAd68-GFP/UnCh group. (B), Serum binding IgG antibody titers (ELISA) at days 0, 28, 56 and 61. The symbols denote individual animals; bars show mean ± SD. Statistics: one-way ANOVA with Tukey’s multiple-comparisons test (* p < .05; ** p < .01; *** p < .001; **** p < .0001).
    Figure Legend Snippet: ChAd68-PreF elicits robust anti-RSV F binding IgG responses in cotton rats. (A), immunization and challenge schedule. Animals received a homologous prime-boost (day 0 and 28) and were intranasally challenged with 1 × 10 5 PFU RSV A2 on day 56, except the unchallenged ChAd68-GFP/UnCh group. (B), Serum binding IgG antibody titers (ELISA) at days 0, 28, 56 and 61. The symbols denote individual animals; bars show mean ± SD. Statistics: one-way ANOVA with Tukey’s multiple-comparisons test (* p < .05; ** p < .01; *** p < .001; **** p < .0001).

    Techniques Used: Binding Assay, Enzyme-linked Immunosorbent Assay

    ChAd68-PreF induces strong neutralization antibody titers against RSV A and RSV B subtypes. serum 60% plaque-reduction neutralization titers (PRNT 60 ) against RSV A2 (A), RSV B (B) and RSV Long (C) determined at days 0, 56 and 61. Symbols represent individual cotton rats; bars show mean ± SD. Statistics: data were log-transformed and analyzed by two-way repeated measures ANOVA with Tukey’s multiple-comparisons test, considering treatment group and time as factors (* p < .05; *** p < .001; **** p < .0001).
    Figure Legend Snippet: ChAd68-PreF induces strong neutralization antibody titers against RSV A and RSV B subtypes. serum 60% plaque-reduction neutralization titers (PRNT 60 ) against RSV A2 (A), RSV B (B) and RSV Long (C) determined at days 0, 56 and 61. Symbols represent individual cotton rats; bars show mean ± SD. Statistics: data were log-transformed and analyzed by two-way repeated measures ANOVA with Tukey’s multiple-comparisons test, considering treatment group and time as factors (* p < .05; *** p < .001; **** p < .0001).

    Techniques Used: Neutralization, Transformation Assay

    ChAd68-PreF protects cotton rats from RSV A2 challenge. (A) and (B), infectious virus titers (Pfu/g tissue) in lung (A) and nasal (B) homogenates 5 days after challenge (day 61). Virus titers in the lungs and noses of cotton rats were assayed by plaque forming units per gram of tissue on day61. (C), RSV NS1 gene copies (RT-qPCR) in lung RNA on day 61. Dashed lines in (C) indicate the estimated detection threshold and the estimated LLOQ. Symbols represent individual animals; bars show mean ± SD. Statistics: two-way repeated measures ANOVA with Tukey’s multiple-comparisons test, considering treatment group and time as factors (* p < .05; **** p < .0001).
    Figure Legend Snippet: ChAd68-PreF protects cotton rats from RSV A2 challenge. (A) and (B), infectious virus titers (Pfu/g tissue) in lung (A) and nasal (B) homogenates 5 days after challenge (day 61). Virus titers in the lungs and noses of cotton rats were assayed by plaque forming units per gram of tissue on day61. (C), RSV NS1 gene copies (RT-qPCR) in lung RNA on day 61. Dashed lines in (C) indicate the estimated detection threshold and the estimated LLOQ. Symbols represent individual animals; bars show mean ± SD. Statistics: two-way repeated measures ANOVA with Tukey’s multiple-comparisons test, considering treatment group and time as factors (* p < .05; **** p < .0001).

    Techniques Used: Virus, Quantitative RT-PCR



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    Image Search Results


    ChAd68-PreF elicits robust anti-RSV F binding IgG responses in cotton rats. (A), immunization and challenge schedule. Animals received a homologous prime-boost (day 0 and 28) and were intranasally challenged with 1 × 10 5 PFU RSV A2 on day 56, except the unchallenged ChAd68-GFP/UnCh group. (B), Serum binding IgG antibody titers (ELISA) at days 0, 28, 56 and 61. The symbols denote individual animals; bars show mean ± SD. Statistics: one-way ANOVA with Tukey’s multiple-comparisons test (* p < .05; ** p < .01; *** p < .001; **** p < .0001).

    Journal: Human Vaccines & Immunotherapeutics

    Article Title: Mucosal immunization with an adenoviral vector expressing a prefusogenic F protein protects the upper and lower respiratory tracts of cotton rats against live respiratory syncytial virus challenge

    doi: 10.1080/21645515.2026.2623573

    Figure Lengend Snippet: ChAd68-PreF elicits robust anti-RSV F binding IgG responses in cotton rats. (A), immunization and challenge schedule. Animals received a homologous prime-boost (day 0 and 28) and were intranasally challenged with 1 × 10 5 PFU RSV A2 on day 56, except the unchallenged ChAd68-GFP/UnCh group. (B), Serum binding IgG antibody titers (ELISA) at days 0, 28, 56 and 61. The symbols denote individual animals; bars show mean ± SD. Statistics: one-way ANOVA with Tukey’s multiple-comparisons test (* p < .05; ** p < .01; *** p < .001; **** p < .0001).

    Article Snippet: Neutralization assays in cotton rats were performed using the following strains: RSV A2 (ATCC VR-1540), RSV B (strain 18537; ATCC VR-1580PQ), and RSV Long (ATCC VR-26).

    Techniques: Binding Assay, Enzyme-linked Immunosorbent Assay

    ChAd68-PreF induces strong neutralization antibody titers against RSV A and RSV B subtypes. serum 60% plaque-reduction neutralization titers (PRNT 60 ) against RSV A2 (A), RSV B (B) and RSV Long (C) determined at days 0, 56 and 61. Symbols represent individual cotton rats; bars show mean ± SD. Statistics: data were log-transformed and analyzed by two-way repeated measures ANOVA with Tukey’s multiple-comparisons test, considering treatment group and time as factors (* p < .05; *** p < .001; **** p < .0001).

    Journal: Human Vaccines & Immunotherapeutics

    Article Title: Mucosal immunization with an adenoviral vector expressing a prefusogenic F protein protects the upper and lower respiratory tracts of cotton rats against live respiratory syncytial virus challenge

    doi: 10.1080/21645515.2026.2623573

    Figure Lengend Snippet: ChAd68-PreF induces strong neutralization antibody titers against RSV A and RSV B subtypes. serum 60% plaque-reduction neutralization titers (PRNT 60 ) against RSV A2 (A), RSV B (B) and RSV Long (C) determined at days 0, 56 and 61. Symbols represent individual cotton rats; bars show mean ± SD. Statistics: data were log-transformed and analyzed by two-way repeated measures ANOVA with Tukey’s multiple-comparisons test, considering treatment group and time as factors (* p < .05; *** p < .001; **** p < .0001).

    Article Snippet: Neutralization assays in cotton rats were performed using the following strains: RSV A2 (ATCC VR-1540), RSV B (strain 18537; ATCC VR-1580PQ), and RSV Long (ATCC VR-26).

    Techniques: Neutralization, Transformation Assay

    ChAd68-PreF protects cotton rats from RSV A2 challenge. (A) and (B), infectious virus titers (Pfu/g tissue) in lung (A) and nasal (B) homogenates 5 days after challenge (day 61). Virus titers in the lungs and noses of cotton rats were assayed by plaque forming units per gram of tissue on day61. (C), RSV NS1 gene copies (RT-qPCR) in lung RNA on day 61. Dashed lines in (C) indicate the estimated detection threshold and the estimated LLOQ. Symbols represent individual animals; bars show mean ± SD. Statistics: two-way repeated measures ANOVA with Tukey’s multiple-comparisons test, considering treatment group and time as factors (* p < .05; **** p < .0001).

    Journal: Human Vaccines & Immunotherapeutics

    Article Title: Mucosal immunization with an adenoviral vector expressing a prefusogenic F protein protects the upper and lower respiratory tracts of cotton rats against live respiratory syncytial virus challenge

    doi: 10.1080/21645515.2026.2623573

    Figure Lengend Snippet: ChAd68-PreF protects cotton rats from RSV A2 challenge. (A) and (B), infectious virus titers (Pfu/g tissue) in lung (A) and nasal (B) homogenates 5 days after challenge (day 61). Virus titers in the lungs and noses of cotton rats were assayed by plaque forming units per gram of tissue on day61. (C), RSV NS1 gene copies (RT-qPCR) in lung RNA on day 61. Dashed lines in (C) indicate the estimated detection threshold and the estimated LLOQ. Symbols represent individual animals; bars show mean ± SD. Statistics: two-way repeated measures ANOVA with Tukey’s multiple-comparisons test, considering treatment group and time as factors (* p < .05; **** p < .0001).

    Article Snippet: Neutralization assays in cotton rats were performed using the following strains: RSV A2 (ATCC VR-1540), RSV B (strain 18537; ATCC VR-1580PQ), and RSV Long (ATCC VR-26).

    Techniques: Virus, Quantitative RT-PCR